8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline (CAS No: 100331-89-3) is a key pharmaceutical intermediate used in the synthesis of APIs Indacaterol acetate and Indacaterol maleate. This compound serves as an essential raw material in API development and synthesis. Explore detailed chemical properties, molecular data, structure information, and verified global suppliers, manufacturers, and distributors of this API intermediate on apicule.
Alternate Names: 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline,1-[8-(benzyloxy)-2-hydroxyquinolin-5-yl]-2-bromoethan-1-one
CAS No: 100331-89-3
PubChem CID: 11667867
Mol Formula: C18H14BrNO3
Mol Weight: 372.2 g/mol
Used in APIs: Indacaterol acetate and Indacaterol maleate
IUPAC Name: 5-(2-bromoacetyl)-8-phenylmethoxy-1H-quinolin-2-one
API Intermediate Description: 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline is a functionalized quinoline derivative used as a synthetic intermediate in medicinal and heterocyclic chemistry.It features a quinoline core bearing a phenolic hydroxyl group, a benzyloxy-protected oxygen at the 8-position, and a reactive 2-bromoacetyl side chain at the 5-position. The bromoacetyl moiety is a strong electrophile, enabling further transformations such as nucleophilic substitution or heterocycle construction, while the benzyloxy group serves as a temporary protecting group during multistep synthesis.
